A compelling study presented at ARVO 2024 by Mohamed Abdouh entitled “Blue Light-Induced Mitochondrial Oxidative Damage Underlay Retinal Pigment Epithelial Cell Apoptosis”, reveals that blue light exposure induces significant oxidative stress in retinal pigment epithelial (RPE) cells, leading to mitochondrial damage and apoptosis (see model). These findings are crucial as they elucidate the mechanisms by which blue light contributes to the progression of age-related macular degeneration (AMD). Mohammed’s study also suggests that new avenues for therapeutic intervention might involve the use of anti-oxidants like N-acetyl cysteins (NAC) and the use of blue-light filtering intraocular lenses. To visualize the model and to know more about this Hot Topic, click here.

In recent years, research interest in conjunctival intraepithelial neoplasia (CIN), has increased. Emily Marcotte's presentation at ARVO 2024 highlighted the importance of understanding CIN's epidemiology and pathology. Her work, entitled “Conjunctival Intraepithelial Neoplasia: A Clinicopathological Study of 250 Patients” was honored with an Arno Habicht Award for Research Sciences at PARD 2024. It underscores the relevance of early detection and management in preventing its progression to invasive carcinoma.

Morgan Yurchuk's poster presentation at ARVO 2024, titled "The Importance of Early Diagnosis of Sebaceous Cell Carcinoma of the Eyelid," was honoured with awards at PARD 2024. This research underscores the critical significance of prompt pathological evaluation in cases of Sebaceous Cell Carcinoma (SCC). Yurchuk's study, analyzing 62 cases, emphasizing the necessity for accurate diagnosis. Notably, the study identifies key prognostic factors such as pagetoid spread and underscores the utility of immunohistochemical markers like adipophilin.

Amid global discussions on sustainability, the medical field has become a key focus, recognizing its significant impact on the environment. Our team, exploring sustainability in surgical, research, and clinical settings, is leading efforts to reduce our environmental footprint. From saving energy to managing waste better, we're coming up with new ideas to make our environment greener.